dr.ir. Peter Spijker

Eindhoven University of Technology
Department of Biomedical Engineering
Biomodeling and Bioinformatics

E-mail:
Tel: +31 40 247 5573
Fax: +31 40 247 2740

Biography

Peter Spijker studied Biomedical Engineering at the Eindhoven University of Technology in the Netherlands and graduated in December 2004 with his master thesis entitled "Dynamic Behaviour of the B2-Adrenergic Receptor" in the group of professor Peter Hilbers. His master thesis research was performed at the California Institute of Technology, Pasadena, United States, at the Materials and Process Simulation Center under direction of professor William A. Goddard III. For his research at the California Institute of Technology Peter received a Fulbright grant supported by the Netherland-America Foundation and the United States Institute of International Education. Currently Peter is working as a PhD-student in the BioModeling and bioInformatics group of professor Peter Hilbers. His research focuses on the development of coarse grained molecular dynamics methods for membrane proteins, hybride molecular dynamics methods to incorporate different time and length scales, as well as new methods in molecular dynamics simulations, such as stochastic boundary conditions and grand canonical ensembles.


Publications

  • A.F. Smeijers, A.J. Markvoort, K. Pieterse, P. Spijker, P.A.J. Hilbers, Coarse Grained Molecular Dynamics Simulations of the Fusion of Vesicles Incorporating Water Channels, Biophys J, 90(1), S29A, (2006)
  • P. Spijker, N. Vaidehi, P.L. Freddolino, P.A.J. Hilbers, W.A. Goddard III, Dynamic Behavior of Fully Solvated B2-Adrenergic Receptor Embedded in the Membrane with Bound Agonist or Antagonist, Proc. Nat. Acad. Sci., 103(13), 4882-4887, (2006)
  • N. Vaidehi, Y.S. Kalani, S.E. Hall, P.L. Freddolino, R.J. Trabanino, W.B. Floriano, P. Spijker, W.A. Goddard III, First principles structure and function prediction for G-protein coupled receptors, Biophys J, 88(1), S357A, (2005)
  • A.J. Markvoort, K. Pieterse, M.N. Steijaert, P. Spijker, P.A.J. Hilbers, The Bilayer-Vesicle Transition Is Entropy Driven, J. Phys. Chem. B, 109, 22649-22654, (2005)